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A 50-year-old woman was admitted to the emergency room (ED) with progressive weakness and ascending numbness of the body, back pain, dysphagia, and diplopia for two days. The neurological findings were preceded by an upper respiratory tract infection. Subsequently, severe weakness of the bulbar and limb muscles, areflexia, and ophthalmoplegia developed. Based on clinical features, Miller-Fisher syndrome (MFS) was diagnosed, while a nerve conduction study revealed an overlap with acute motor-sensory axonal neuropathy (AMSAN) variant Guillain-Barre syndrome (MFS/AMSAN-GBS). The panel of anti-ganglioside antibodies was positive. Early treatment with intravenous immunoglobulin favored the outcome. |
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